It would be impossible to write about anabolic steroids without a reference to the golden age of bodybuilding. I really should have continued this for another three week cycle but again, sometimes there are other priorities in life that take (and should take) precedence over supplements and it's difficult to justify the price when you're already spending a pretty penny on your staple supplements such as protein, glutamine, and vitamins.
These proliferate, become different and merge, generating myotubes that are attached to a pre-existing fiber, or form a new functional muscle fiber 10 - 12 For that, a complex set of cell responses is activated, which leads to the proper regeneration of the Decaduro injured tissue and to a well innervated muscle, which is vascularized and has an intact contractile system 13 Therefore, the process of muscle repair is well described in literature, but its association with the use of anabolic steroids is not very clear.
These perceptions were enhanced by the passage of the Anabolic Steroid Control Act of 2004 that listed anabolic steroids as schedule III controlled substances—similar to ketamine, opiates and morphine ( 6 ). This policy mandated that a physician prescription was necessary to obtain the medication; further challenging the opinion of the general public.
Even though Deca has relatively low androgenic effects, these are still powerful on the female body and while not all women using Deca at low doses will experience virilization, when it does occur the long acting Nandrolone Decanoate will take several weeks to clear the system and have these effects reversed; this is a reason that women considering Deca may use the shorter acting Nandrolone Phenylpropionate ester instead.
The most documented side effects of anabolic-androgenic steroids abuse are those on liver, including structural and functional alterations such as cholestatic jaundice, peliosis hepatitis, hepatocellular hyperplasia, and hepatocellular adenoma ( Shoupe & Lobo 1984 ). In addition, other alterations are frequently documented, such as decreased HDL and increased LDL, which are involved in atherosclerosis and peripheral vascular disease.
Stacking Deca with testosterone is something highly advised by many of the people who have had the best results with it. A cycle that utilizes testosterone in 500mg weekly doses can benefit greatly from utilizing Deca Durabolin in 400mg weekly doses.
On the other hand, animals treated with high doses of testosterone have decreased glucose disposal rates ( Hollmang & Bjorntorp 1992 ). Bodybuilders, who self-administer SDs of anabolic-androgenic steroids, have diminished glucose tolerance and increased insulin resistance ( Shoupe & Lobo 1984 , Cohen & Hickman 1987 ). However, some studies report normal glucose metabolism when high anabolic-androgenic steroids doses are used in rats.
Looking further into this, we can also see that Nandrolone experiences aromatization into Estrogen in the liver, but in areas of the body where there is normally a high degree of Estrogen conversion (in fat tissue, for instance), Deca is considerably resistant here4.
Due to these traits, Deca Durabolin is well known for promoting joint relief, and for many athletes that's the only reason they'll use it. Due to these traits, as well as its ability to increase red blood cell count, we can begin to see what types of therapeutic advantages this steroid can hold.
Joint pain reduction is perhaps one of the most famous benefit of using Deca Durabolin and every heavy lifter deeply appreciates it. The beneficial effects of Deca Durabolin on your joints would allow you to push further, making you get less pains and therefore the lifts you can tolerate are increased.
Kamanga-Sollo et al. 27 studied the culture of Bovine Satellite Cells (BSC) treated with androgens and observed that the treatment of BSC cultures increased mRNA IGF-I expression and proliferation, thus establishing that steroids have direct anabolic effects.